Aegis Sciences CIO on Scaling IT to Meet COVID Testing Demand

Victoria D. Doty

Toxicology lab finds versatile way to scale up its methods that also lower prices whilst escalating the rate of tests.

Faced with a need to ramp up its tests capability speedy amid the pandemic, Aegis Sciences crafted a approach to develop up its IT infrastructure and platforms from within just as very well as by tapping third-get together methods. The toxicology lab already furnished companies monitoring for drug interactions and other forensic lab sciences. The immediacy and scope of tests for COVID-19 arrived not prolonged after Aegis commenced its individual restoration from a devastating, severe climate occasion in 2020 that afflicted its group in Nashville, Tennessee.

Image: zinkevych -

Impression: zinkevych –

CIO Tim Ryan spoke with InformationWeek about the method Aegis put into action to recover from the disruption of an real twister and then adapt its IT infrastructure to scale up from 3,500 day-to-day tests for COVID to sixty,000 tests per working day to satisfy a grant from the Countrywide Institutes of Wellness.


What was the IT method for Aegis Sciences in advance of COVID-19 struck?

Pre-pandemic, we have two labs. Our key lab, which is our toxicology lab, and across the parking great deal is our administrative setting up, which housed at the time a very modest biopharma lab. Our tox lab generally would get anywhere concerning 3,800 to 4,500 samples working day. That was our major company. Our biopharma lab did a very modest amount of money of company and really wasn’t a aspect in our operations.

We had a twister in Nashville that happened final March, which prompted a great deal of disruption to our company. As we were being coming out of the twister scenario, the pandemic hit comprehensive throttle and national lockdowns begun to come about. We made the decision in March to see if we could get into the COVID tests.

On the tox aspect of the company, we obtained hit noticeably by the lockdowns. Doctors’ offices weren’t open. Behavioral well being clinics shut down. It had a significant effects.


What items did you put collectively for your going forward approach?

The 1st point we had to do was see if we could get the COVID examination up and jogging for 3,500 specimens. We had to be in a position to report to every single states’ division of well being. No matter whether you are doing 3,500 or 100,000 tests, you however have to have connectivity to these states. We desired to ascertain how we were being going to link to the states from a reporting perspective. You had fax, CSV documents, and HL7 (Wellness Stage seven) electronic resulting documents. That was really dependent on how the states could handle it. Sad to say, there is no one common for all of the states. That creates complexities.

One more point we had to offer with was how to get benefits out to patients. Being a toxicology lab, there’s not a large need to have a affected person portal. We had to ascertain if we could develop our individual affected person portal or was that a little something we desired to outsource. We ended up choosing that setting up the portal ourselves would be more quickly and a lot less high-priced.

Tim Ryan, Aegis Sciences

Tim Ryan, Aegis Sciences


What criteria were being designed in conditions of internal methods and workers with the capabilities to make this perform?

We had a third get together assigned as very well. By the time we had a agreement with a vendor to develop it for us, we were being very well on way with our evidence of notion and then were being immediately in a position to total the internal affected person portal where by we no for a longer period desired third-get together assistance.


What even further actions did you have to just take?

We have a third-get together laboratory info management technique (LIMS). We also desired to ascertain internal capability on that technique. When the 3,500-capability limit was mentioned, we were being confident we could soak up that. Just after we were being prosperous, there was a large need in the country. As we were being escalating the company aspect, we also desired to seem at the IT aspect. As we scaled up, we were being in a position to just take gain of what Pure Storage delivers. One particular of the gains of going with Pure is their Evergreen abilities.

Our LIMS is an Oracle-based technique. Earlier we had storage that was dedicated just to LIMS based on our Oracle licensing. Thus, that would lessen our Oracle prices for the reason that we could not have a shared infrastructure for the reason that you’d have to pay the Oracle prices for that shared infrastructure. We worked with our LIMS vendor, ended up obtaining an software-based Oracle license where by we could use Oracle as prolonged as it was just for that software versus an business-based license.

That enabled us to go our LIMS technique to have a Pure backend and we did not have to worry about our licensing prices going forward if we ongoing to scale additional in the long term. That gave us a great deal of overall flexibility. We saved several millions of dollars working with that product.

We also ended up obtaining funding, $six.six million, from NIH’s RADx (Swift Acceleration of Diagnostics) program. That was to develop out to sixty,000 tests a working day at first.

We had already instituted Microsoft Teams prior to the pandemic and obtained a rehearsal with the twister as people today were being functioning from home. We ended up going business-huge with our Teams software, so we did not have to carry IT methods into the setting up. We completely deployed to sixty,000 by the finish of September.

As aspect of that $six.six million grant, there was a significant portion that was IT linked. That served us fund purchasing more Pure abilities as very well as other internal abilities. We had some complex financial debt that would stop us from moving forward. We were being in a position to mitigate that to aid us grow our capability. NIH was very joyful with the benefits and we have observed given that agreed to go to one hundred ten,000 tests per working day capability. We gained a further $six million in NIH funding to aid us grow not only the IT techniques but also our laboratory.


For additional linked information, observe up with these stories:

What Comes Upcoming for the COVID-19 Computing Consortium

The Role of AI in the Race for a Coronavirus Vaccine

Supercomputers Recruited to Perform on COVID-19 Investigate


Joao-Pierre S. Ruth has put in his vocation immersed in company and technological know-how journalism 1st covering nearby industries in New Jersey, afterwards as the New York editor for Xconomy delving into the city’s tech startup group, and then as a freelancer for this kind of stores as … See Full Bio

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